We are seeking for candidates for a PhD fellowship on the topic: Decoding movement goals and muscle activation patterns from neural activity
This project will be co-directed by Bjorg Kilavik (Timone Neuroscience Institute) and Demian Battaglia (Institute for Systems Neuroscience) at Aix-Marseille University, awarded the prestigious status of “Excellence Initiative” (A*MIDEX) by the French Government and considering interdisciplinary studies as one of its main axes of growth.
The cerebral cortex is organized into multiple layers comprising largely distinct distributions of incoming and outgoing anatomical projections. It is not clear however which of these layers is the better target for Brain Machine Interface (BMI) applications aiming at driving screen cursors or robotic prostheses via the decoding of motor plans and commands from motor cortical activity.
In this project, we will start by determining the availability of information about movement goal vs. muscle activation patterns in different motor cortical layers, by doing offline decoding of existing and future higher-quality laminar data recorded in NHPs. In parallel, we will build an online BMI setup for further experiments, coupled with a NHP upper limb exoskeleton already on site. We will first use information theory approaches to systematically compare the amount of information relevant for different applications that can be potentially extracted from different laminar depths (superficial vs. deep) and/or types of signal (spike trains, local field potentials). Based on these offline analyses, we will then design optimized fast-to-compute features suitable for online decoding. These results will allow us to optimise the harvesting of signals and their use for motor BMI applications.
The englobing experimental research program is ongoing, and essential equipment is already in place. When the student arrives, data is already available for analyses, and recordings will immediately start in a newly trained animal. The two supervisors are highly complementary, with renowned expertise in experimental (Kilavik) and computational (Battaglia) approaches, and can therefore provide a solid support for the student to succeed in this highly demanding project.
Candidate profile: Candidates with a background in biology, neuroscience, physics or engineering are particularly encouraged to apply. The work will combine experimental and computational approaches, with adequate supervision from the highly complementary supervisors. This project provides an excellent opportunity to gain solid multidisciplinary training at the forefront of integrative neurosciences.
The scholarships are open to Master graduate students from top ranked non-French universities.
The application must include :
• a detailed curriculum
• a letter of motivation
• two recommandation letters (the referee should use the template “phd evaluation form” )
• the template “choice of research projects” (applicants must select and rank two of the proposed research projects)
Applications should be sent before May 21st, 2017 at midnight (French time).
The Pradhan Lab in the Department of Psychiatry, University of Illinois at Chicago (UIC), seeks an outstanding Postdoctoral Research Associate to study the neurobiology of opioid receptors. This is a full-time, NIH funded position for a period of 2-3 years. The successful candidate will investigate the role of opioid receptors in chronic migraine and other pain disorders; and will use state of the art genomic and proteomic approaches, bioinformatics and animal behavioral models.
Applicants with expertise in pain or addiction biology, and a track record of publication are particularly encouraged to apply.
Candidates should have a recent PhD in biomedical sciences. Interested candidates should send an updated CV/resume and contact information for 3 references by July 15, 2017 to Amynah Pradhan; firstname.lastname@example.org. University of Illinois at Chicago is an Affirmative Action/Equal Opportunity Employer
Amynah Pradhan PhD
Department of Psychiatry UIC
1601 W Taylor St.
Chicago IL 60612
The Department of Anesthesiology and Washington University Pain Center seeks an Postdoctoral Research Fellow for a trained behavioral pharmacologist and biochemist/molecular biologist to study mechanisms underlying opioid dependence and to examine the interaction between pain and opioid misuse (see Fakira et al., 2014 Biological Psychiatry; Portugal et al., 2014 Journal of Neuroscience; Hipolito et al., 2015 Journal of Neuroscience; Fakira et al., 2016 Neuropsychopharmacology). The laboratory integrates the study of the molecular and cellular changes induced by drugs of abuse using a combination of state-of-art behavioral, optogenetics, chemogenetics approaches in combination with electrophysiological analyses. For more details see lab web page (http://elysium.wustl.edu/moron-concepcion_lab/).
Candidates must have a PhD in neuroscience, biochemistry, pharmacology or biomedical sciences. Experience with behavioral pharmacology expertise, opto/chemogenetics, molecular biology, biochemical techniques is required. The successful candidate should be able to work independently and be willing to collaborate with the groups of Dr Rob Gereau and Michael Bruchas at the Department of Anesthesiology. Interested candidates should also forward their CV and names of 3 references to: Jose A. Morón Concepción, PhD, Associate Professor, Depts of Anesthesiology & Neuroscience, Washington University School of Medicine, E-mail: email@example.com.
The MNS Council has selected 3 proposals for symposia at the next FENS forum in Berlin (http://www.forum2018.fens.
Please read the enclosed pdf file
Assistant, Associate or Full Professor of pharmacology/toxicology for a full-time, 12-month position available at the University of Mississippi.
The University of Mississippi School of Pharmacy, Department of BioMolecular Sciences is searching for an currently open. We seek candidates with expertise in cardiovascular biology, cancer biology, neuroscience/drugs of abuse, or infectious diseases. The candidates should demonstrate a distinguished and innovative research program (as evidenced by a significant publication record and the potential to secure extramural funding) and teaching experience. Applicants applying for the higher ranks should have a nationally-recognized research program with recurrent success in securing extramural funding and excellent teaching credentials.
The University of Mississippi is the flagship university for the State of Mississippi, and is a Carnegie R1 research university. The School of Pharmacy is on the main campus in Oxford, a community of approximately 19,000 residents that has been recognized nationally as one of America’s best places to live. The Chronicle of Higher Education has named The University of Mississippi as one of the “Great Colleges to Work For.” The Department of BioMolecular Sciences has 14 full-time faculty with research emphases in pharmacology, environmental toxicology, medicinal chemistry, and pharmacognosy. The faculty have affiliations with the Research Institute of Pharmaceutical Sciences and collaborative opportunities in the National Center for Natural Products Research. The department has teaching responsibilities in the Pharm.D. (Doctor of Pharmacy) program as well as in the M.S. and Ph.D. programs in Pharmaceutical Sciences.
Job Responsibilities: To carry out research, teaching and service within the Department of BioMolecular Sciences
A Ph.D. in Pharmacology, physiology, toxicology or a related field and postdoctoral research experience is required.
Applicants should provide a letter of application outlining their qualifications for the position and also submit: a curriculum vitae; a five-page or less statement of future research plans; a statement of teaching philosophy; a list of teaching experience, specialties, and competencies; and the names and contact information of four references. We strongly encourage applicants from all underrepresented groups. Applications must be submitted through The University of Mississippi’s online employment site at https://jobs.olemiss.edu.
For additional information please contact, Prof. Zia Shariat-Madar, Search Committee Chair, firstname.lastname@example.org, 662-915-5150.
We recently discovered that growth factor inhibition completely eliminates opioid tolerance. We also discovered an important reason why opioids are ineffective against neuropathic pain and demonstrated a mechanistic link between pain and tolerance. However, we still do not fully understand the mechanisms underlying these remarkable effects. There are many opportunities for creative, driven individuals to make seminal contributions early in their careers. We are attacking these problems using Drosophila and mouse genetics, signal transduction assays, proteomics, as well as advanced behavioral and neuroanatomical techniques. We interact with stimulating collaborators in a high caliber research environment at the world-renowned Pittsburgh Center for Pain Research. Important publications:
Babcock, DT, Shi, S, Shaw. M, Gutstein, HB and Galko, MJ: Hedgehog signaling regulates nociceptive sensitization, Current Biology, 27:1525, 2011
Wang, Y, Barker, KE, Shi, S, Diaz, MF, Mo, B, and Gutstein, HB: Blockade of morphine-induced PDGFR-b activation eliminates morphine analgesic tolerance, Nature Medicine, 18:385, 2012
Donica, CL, Cui, Y, Shi, S, and Gutstein, HB: PDGFR-b antagonism restores morphine analgesic efficacy against neuropathic pain, PLoS ONE 9(5): e97105. doi:10.1371/journal.pone.0097105, 2014
Please send your CV, a summary of research experience along with the names and contact information for three references to:
Howard B. Gutstein, M.D.
Departments of Anesthesiology and Neurobiology, University of Pittsburgh School of Medicine
A-1305 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261 USA